Does the Virtual Server IP need to be in the same subnet as nodes and cluster

Scenario:

Node1 IP = 10.10.10.11

Node2 IP = 10.10.10.12

Cluster IP = 10.10.10.13

Default gateway IP = 10.10.10.1

Subnet = 255.255.255.0

Can I have Virtual Server Name IP not in 10.10.10.XXX subnet (e.g. 10.10.20.20)?  Since the default gateway will be different will that not cause issues?  This is in the same LAN.